Artículos científicos

Figueroa JD et al. Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry. Hum Mol Genet 2016; 25: 1203-14.

Sampson JN et al. Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. J Natl Cancer Inst 2015;107 (12):djv279. doi: 10.1093/jnci/djv279.

Espejo-Herrera N et al. Nitrate in drinking water and bladder cancer risk in Spain. Environ Res 2015;137:299-307.

Figueroa JD et al. Modification of Occupational Exposures on Bladder Cancer Risk by Common Genetic Polymorphisms. J Natl Cancer Inst. 2015;107(11). pii: djv223. doi: 10.1093/jnci/djv223.

Wang Z et al. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Hum Mol Genet. 2014; 23:6616-33.

Salas LA et al N.LINE-1 methylation in granulocyte DNA and trihalomethane exposure is associated wit000h bladder cancer risk. Epigenetics. 2014. 1532-9.

Fu YP et al. The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease. Cancer Res. 2014;74(20):5808-18.

Tajuddin SM et al. LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk. Br J Cancer. 2014;110:2123-30.

Serra-Majem L et al. Chinchón declaration; decalogue on low- and no-calorie sweeteners (LNCS). Nutr Hosp. 2014;29:719-34.

Figueroa JD et al. Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet. 2014 ;23:1387-98.

Salas LA et al. Biological and statistical approaches for modeling exposure to specific trihalomethanes and bladder cancer risk. Am J Epidemiol. 2013;178:652-60.

Tajuddin SM et al. Spanish Bladder Cancer/EPICURO Study Investigators. Genetic and non-genetic predictors of LINE-1 methylation in leukocyte DNA. Environ Health Perspect. 2013;121:650-6.

García Closas R et al.. Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer. Cancer Res. 2013;73:2211-20.

Robles C et al. Bladder cancer and seroreactivity to BK, JC and Merkel cell polyomaviruses: the Spanish bladder cancer study. Int J Cancer. 2013;133: 597-603.

Tang W et al. Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer. Hum Mol Genet 2012; 21:1918-30.

Fu YP et al. Common genetic variants in the PSCA gene influence gene expression and bladder  cáncer risk. Proc Natl Acad Sci U S A. 2012; 109: 4974-9.

Menashe I et al. Large-scale pathway-based analysis of bladder cancer genome-wide association data from five studies of European background. PLoS One 2012; 7(1):e29396.

García Closas R et al. A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. Hum Mol Genet 2011; 20: 4282-9.

Castaño-Vinyals G et al. Socioeconomic status and exposure to disinfection by-products in drinking water in Spain. Environ Health 2011; 10:18.

Alguacil J et al. Urinary pH, Cigarette Smoking and Bladder Cancer Risk. Carcinogenesis. 2011; 32: 843-7.

Rothman N et al. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet. 2010; 42:978-84.

Cantor K et al. Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection Byproducts, and Risk of Bladder Cancer in Spain. Environ Health Perspect 2010; 118: 1545-50.

García Closas R. Nutrición y Enfermedad de Alzheimer. Alzheimer Real Invest Demenc 2010; 46: 24-36.

Guey LT et al. Genetic susceptibility to distinct bladder cancer subphenotypes. Eur Urol 2010; 57: 283-92.

Huang AT et al. Bladder cancer and reproductive factors among women in Spain. Cancer Causes Control 2009;20: 1907-13.

Villanueva CM et al. Determinants of quality of interview and impact on risk estimates in a case-control study of bladder cancer. Am J Epidemiol 2009 170:237-43.

Luque V, et al. Subcutaneous fat stores related to weight in full-term neonates. Ann Hum Biol 2009; 36: 88-97.

Castillejo A, et al. TGFB1 and TGFBR1 polymorphic variants in relationship to bladder cancer risk and prognosis. Int J Cancer 2009; 124: 608-13.

Villanueva CM et al. Coffee consumption, genetic susceptibility and bladder cancer risk. Cancer Causes Control 2009; 20: 121-7.

Figueroa JD et al. Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes. Carcinogenesis 2008; 29: 1955-62.

Samanic CM, et al. Occupation and bladder cancer in a hospital-based case-control study in Spain. Occup Environ Med 2008; 65(5): 347-53.

Silverman DT et al. Does increased urination frequency protects against bladder cáncer? Int J Cancer 2008; 123:1644-8.

Moore LE et al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol 2008; 9:359-66.

Espinoza F et al. Micronuclei assessment in the urothelial of women using hair dyes and its modulation by genetic polymorphisms. Cancer Lett 2008; 263: 259-66.

Castaño-Vinyals G et al. Air polution and risk of urinary bladder cancer in a case-control study in Spain. Occup Environ Med 2008; 65: 56-60.

Serra C et al. Work in the textile industry in Spain and bladder cancer. Occup Environ Med. 2008; 65(8): 552-9.

Castaño-Vinyals G et al. Bulky DNA adduct formation and risk of bladder cancer. Cancer Epidemiol Biomarkers Prev 2007; 16: 2155-9.

Michaud DS et al. Total fluid intake and the joint effect of expossure to desinfection by-products on risk of bladder cancer. Environmental Health Perspectives 2007; 115: 1569-72.

Figueroa J et al. Evaluation of genetic variation in the double-strand break repair pathway and bladder cancer risk Carcinogenesis 2007; 28: 1788-93.

Murta-Nascimento C et al. Risk of bladder cancer associated with family history of cancer. Do low penetrance polymorphisms account for the increase in risk? Cancer Epidemiol Biomarkers Prev 2007; 16; 1595-600.

García Closas R, et al. Food, nutrient and heterocyclic amine intake and the risk of bladder cancer. Eur J Cancer 2007; 43; 1731-40.

Lubin JH et al. Evidence for an intensity dependent interaction of NAT2 acetylation genotype and cigarette smoking in the Spanish Bladder Cancer Study. Int J Epidemiol 2007; 36: 236-41.

García Closas R et al. Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk. PLoS Genet 2007; 23:  e29.

Moore LE et al. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer. Int J Cancer 2007; 120: 2452-8.

Figueroa JD et al. Genetic variation in the base excision repair pathway and bladder cancer risk. Hum Genet 2007; 121: 233-42.

Villanueva CM et al. Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in pools. Am J Epidemiol 2007; 165: 148-56.

Fortuny J et al. Use of analgesics and nonsteroidal anti-inflammatory drugs, genetic predisposition, and bladder cancer risk in Spain. Cancer Epidemiol Biomarkers Prev 2006; 16: 1696-702.

Samanic C et al. Smoking and bladder cancer risk in Spain: effects of tobacco type, timing, environmental tobacco smoke, and gender. Cancer Epidemiol Biomarkers Prev 2006; 15: 1348-54.

Kogevinas M et al. Hair dye use is not associate with risk for bladder cancer: evidence from a case-control study in Spain. Eur J Cancer 2006; 42: 1448-54.

Villanueva CM et al. Assessment of lifetime exposure to trihalometanes through different routes. Occup Environ Med 2006; 63: 273-7.

García Closas R et al. Genetic variation in the nucleotide excision repair pathway and bladder cancer risk. Cancer Epidemiol Biomarkers Prev 2006; 15: 536-42.

García Closas R, Berenguer A, González CA. Changes in food supply in Mediterranean countries from 1961 to 2001. Public Health Nutrition 2006; 9: 53-60.

García Closas R. La HTA en España: ¿Constituye un problema de Salud Pública?. HTA. Barcelona, 2006.

Fortuny J et al. Use of analgesics and aspirin in a Spanish multicenter study. Gac Sanit 2005; 19(4): 316-20.

García Closas R et al. NAT2 slow acetylation and GSTM1 null genotypes increase bladder cancer risk: results from the Spanish Bladder Cancer Study and meta-analyses. Lancet 2005; 366: 649-59.

García Closas R, Castellsagué X, Bosch FX, González CA. The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence. Int J Cancer 2005; 117: 629-37. – A-

Hernandez S et al. FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: independent distribution and lack of association with prognosis. Clin Cancer Res 2005; 11: 5444-50.

Jakszyn P et al. Development of a food database of nitrosamines, heterocyclic amines and polycyclic aromatic hydrocarbons. Journal of Nutrition 2004; 134: 2011-2014.

García Closas R et al. Dietary sources of vitamin C, vitamin E and specific carotenoids in Spain. British Journal of Nutrition 2004; 91:1005-1011.

Serra-Majem Ll et al. Cyclamate and cyclohexylamine excretion are not related to male fertility in humans. Food Additives and Contaminants 2003; 20: 1097-1104.

Puente D et al Gender-related differences in clinical and pathological characteristics and therapy of bladder cancer. European Urology 2003; 43: 53-62.

Serra-Majem L et al. Comparative analysis of nutrition data from national, household and individual levels: results from a WHO-CINDI collaborative project in Canada, Finland, Poland and Spain. Journal of Epidemiology and Community Health 2003; 57: 74-80.

Serra-Majem L et al. Determinants of nutrient intake among children and adolescents: results from the enKid study.  Annals of Nutrition and Metabolism 2002; 46 (suppl 1): 31-8.

García Closas R et al. Distribución de la concentración sérica de b-caroteno, retinol y a-tocoferol en una muestra representativa de la población adulta de Cataluña.  Medicina Clínica (Barc.) 2002; 118: 256-61.

García Closas R et al. Distribución de la concentración sérica de vitamina C, ácido fólico y vitamina B12 en una muestra representativa de la población adulta de Cataluña.  Medicina Clínica (Barc.) 2002; 118:135-41.

Takkouche B et al. Intake of vitamin C and zinc and risk of common cold: A cohort study. Epidemiology 2002; 13: 38-44.

Takkouche B, Regueira-Méndez C, García Closas R, Figueiras A, Gestal-Otero JJ, Hernán MA. Intake of wine, beer and spirits and risk of clinical common cold. American Journal of Epidemiology 2002; 155: 853-8.

Serra-Majem Ll et al. Food patterns of Spanish schoolchildren and adolescents: The Enkid Study. Public Health Nutrition 2001; 4: 1433-8.

Fernández Ballart J et al. Prevalencia de anemia ferropénica y déficit de hierro en la población adulta de Cataluña. Revista Española de Nutrición Comunitaria 2000; 6: 7-13.

García Closas R et al. Encuestas alimentarias en la  infancia y adolescencia.  Archivos de Pediatría 2000; 51: 146-58.

Serra-Majem Ll, García Closas R. Acerca de la participación en estudios epidemiológicos. Medicina Clínica (Barc.) 2000; 114: 43-4.

García Closas R et al. Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain. Cancer, Causes and Control 1999; 10: 71-5.

Gascón-Vila P et al. Fuentes alimentarias de vitaminas A, C, E y beta-caroteno en una población adulta mediterránea. Gaceta Sanitaria 1999; 13: 22-9.

García Closas R et al. Distribución de la concentración de lípidos séricos  en una muestra representativa de la población adulta de Cataluña. Medicina Clínica (Barc.) 1999; 113: 6-12.

García Closas R et al. The high intake of specific carotenoids and flavonoids does not reduce the risk of bladder cancer. Nutrition and Cancer 1999; 35: 212-4.

Cobos A et al. Which statin is most efficient for the treatment of hypercholesterolemia? A cost-effectiveness analysis. Clinical Therapeutics 1999; 2: 1924-36.

García Closas R, Serra Majem Ll. Factores de riesgo cardiovascular en España: colesterol. Revista Española de Nutrición Comunitaria 1999; 5: 122-5.

Fisac C et al. Limitaciones en la recogida y procesamiento de datos dietéticos (I). Métodos de evaluación del consumo alimentario. Clínica e Investigación en Arteriosclerosis 1998; 10: 32-41.

García Closas R et al. Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain. Nutrition and Cancer 1998; 32: 154-8.

Gascón Vila P et al. Determinants of the nutritional status of vitamin E in a non-smoking mediterranean population. Analysis of the effect of vitamin E intake, alcohol consumption, and BMI on the serum alpha-tocopherol concentration. European Journal of Clinical Nutrition 1997; 51: 723-8.

Serra Majem L, et al. Dieta y enfermedad coronaria en España. ¿Existe la paradoja española?. Alimentación, Nutrición y Salud 1997; 14: 95-105.

García Closas R, Serra Majem Ll. Contribución de la epidemiología a la evaluación del poder cariogénico de la dieta. Revisiones en Salud Pública 1997; 5: 49-68.

García Closas R et al. A cross-sectional study of dental caries, intake of confectionery and foods rich in starch and sugars, and salivary counts of Streptoccocus mutans in children in Spain. American Journal of Clinical Nutrition 1997; 66: 1257-63.

García Closas R et al. Consumo de café y colesterolemia. ¿Relación o confusión?. Medicina Clínica (Barc) 1996; 106: 477-8.

Serra Ll et al. Encuestas de nutrición en poblaciones humanas. Ejecución y recogida de la información. Marcadores biológicos. En: Departamento de Salud Pública. Universidad de Alicante. XII Reunión Científica de la Sociedad Española de Epidemiología. Alicante: Departamento de Salud Pública, Universidad de Alicante, 1994.

Serra-Majem Ll et al. Dietary habits and dental caries in a population of spanish schoolchildren with low levels of caries experience. Caries Research 1993; 27: 488-94.

García Closas R et al. Fish consumption, omega-3 fatty acids and the  Mediterranean diet. European Journal of  Clinical Nutrition 1993; 47 (suppl. 1): 85-90.

Serra Majem Ll et al. Cribado del exceso de peso. Medicina Clínica (Barc.) 1993; 101 (supl. 1): 56-61.

Serra Majem Ll et al. Azúcar y caries: aproximación a la situación epidemiológica en Catalunya y resultados de un estudio transversal. Archivos de Odontoestomatología Preventiva y Comunitaria 1993; 9 (supl. II): 675-86.

García Closas R, Serra Ll. Hàbits dietètics de la població infantil catalana. Infància. Associació de Mestres Rosa Sensat. Barcelona. Febrero, 1992.